Relative rate and location of intra-host HIV evolution to evade cellular immunity are predictable

Human immunodeficiency virus (HIV) evolves within infected persons to escape being destroyed by the host immune system, thereby preventing effective immune control of infection. Here, we combine methods from evolutionary dynamics and statistical physics to simulate in vivo HIV sequence evolution, pr...

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Detalles Bibliográficos
Autores principales: Barton, John P., Goonetilleke, Nilu, Butler, Thomas C., Walker, Bruce D., McMichael, Andrew J., Chakraborty, Arup K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879252/
https://www.ncbi.nlm.nih.gov/pubmed/27212475
http://dx.doi.org/10.1038/ncomms11660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879252/
https://www.ncbi.nlm.nih.gov/pubmed/27212475
http://dx.doi.org/10.1038/ncomms11660

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