TCR signaling by conventional CD4(+) T cells is required for optimal maintenance of peripheral regulatory T cell numbers

To maintain immune tolerance, regulatory T cell (Treg) numbers must be closely indexed to the number of conventional T cells (Tconvs) so that an adequate Treg:Tconv ratio can be maintained. Two factors important in this process are the cytokine interleukin‐2 (IL‐2) and T cell receptor (TCR) stimulat...

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Detalles Bibliográficos
Autores principales: Leichner, Theresa M., Satake, Atsushi, Kambayashi, Taku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879461/
https://www.ncbi.nlm.nih.gov/pubmed/27891224
http://dx.doi.org/10.1002/iid3.100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879461/
https://www.ncbi.nlm.nih.gov/pubmed/27891224
http://dx.doi.org/10.1002/iid3.100

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