Evidence of perturbed germinal center dynamics, but preserved antibody diversity, in end‐stage renal disease

INTRODUCTION: End‐stage renal disease (ESRD) is associated with increased infectious susceptibility and with reduced vaccine responses consistent with compromised humoral immunity. Whether the compromised humoral immunity is due to reduced antibody diversity (reduced somatic hypermutation [SHM]) or...

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Detalles Bibliográficos
Autores principales: Assing, Kristian, Nielsen, Christian, Jakobsen, Marianne, Scholze, Alexandra, Nybo, Mads, Soerensen, Grete, Mortensen, Sussie, Vejen, Knud, Barington, Torben, Bistrup, Claus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879468/
https://www.ncbi.nlm.nih.gov/pubmed/27957330
http://dx.doi.org/10.1002/iid3.108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879468/
https://www.ncbi.nlm.nih.gov/pubmed/27957330
http://dx.doi.org/10.1002/iid3.108

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