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Clinical Trial Simulations From a Model‐Based Meta‐Analysis of Studies in Patients With Advanced Hepatocellular Carcinoma Receiving Antiangiogenic Therapy

A mixed effect model describing median overall survival (mOS) in patients with advanced hepatocellular carcinoma (aHCC) treated with antiangiogenic therapy (AAT) was developed from literature data. Data were extracted from 59 studies, representing 4,813 patients. The final model included estimates o...

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Detalles Bibliográficos
Autores principales: Zierhut, ML, Chen, Y, Pithavala, YK, Nickens, DJ, Valota, O, Amantea, MA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879476/
https://www.ncbi.nlm.nih.gov/pubmed/27299940
http://dx.doi.org/10.1002/psp4.12078