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Pseudomonas aeruginosa Induced Airway Epithelial Injury Drives Fibroblast Activation: A Mechanism in Chronic Lung Allograft Dysfunction

Bacterial infections after lung transplantation cause airway epithelial injury and are associated with an increased risk of developing bronchiolitis obliterans syndrome. The damaged epithelium is a source of alarmins that activate the innate immune system, yet their ability to activate fibroblasts i...

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Detalles Bibliográficos
Autores principales: Borthwick, L. A., Suwara, M. I., Carnell, S. C., Green, N. J., Mahida, R., Dixon, D., Gillespie, C. S., Cartwright, T. N., Horabin, J., Walker, A., Olin, E., Rangar, M., Gardner, A., Mann, J., Corris, P. A., Mann, D. A., Fisher, A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879508/
https://www.ncbi.nlm.nih.gov/pubmed/26714197
http://dx.doi.org/10.1111/ajt.13690