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Pseudomonas aeruginosa Induced Airway Epithelial Injury Drives Fibroblast Activation: A Mechanism in Chronic Lung Allograft Dysfunction
Bacterial infections after lung transplantation cause airway epithelial injury and are associated with an increased risk of developing bronchiolitis obliterans syndrome. The damaged epithelium is a source of alarmins that activate the innate immune system, yet their ability to activate fibroblasts i...
Autores principales: | Borthwick, L. A., Suwara, M. I., Carnell, S. C., Green, N. J., Mahida, R., Dixon, D., Gillespie, C. S., Cartwright, T. N., Horabin, J., Walker, A., Olin, E., Rangar, M., Gardner, A., Mann, J., Corris, P. A., Mann, D. A., Fisher, A. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879508/ https://www.ncbi.nlm.nih.gov/pubmed/26714197 http://dx.doi.org/10.1111/ajt.13690 |
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