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Review: The HSP90 molecular chaperone—an enigmatic ATPase
The HSP90 molecular chaperone is involved in the activation and cellular stabilization of a range of ‘client’ proteins, of which oncogenic protein kinases and nuclear steroid hormone receptors are of particular biomedical significance. Work over the last two decades has revealed a conformational cyc...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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John Wiley and Sons Inc.
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879513/ https://www.ncbi.nlm.nih.gov/pubmed/26991466 http://dx.doi.org/10.1002/bip.22835 |