HIV-dependent depletion of influenza-specific memory B cells impacts B cell responsiveness to seasonal influenza immunisation

Infection with HIV drives significant alterations in B cell phenotype and function that can markedly influence antibody responses to immunisation. Anti-retroviral therapy (ART) can partially reverse many aspects of B cell dysregulation, however complete normalisation of vaccine responsiveness is not...

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Detalles Bibliográficos
Autores principales: Wheatley, Adam K., Kristensen, Anne B., Lay, William N., Kent, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879526/
https://www.ncbi.nlm.nih.gov/pubmed/27220898
http://dx.doi.org/10.1038/srep26478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879526/
https://www.ncbi.nlm.nih.gov/pubmed/27220898
http://dx.doi.org/10.1038/srep26478

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