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Self-assembly of PEGylated tetra-phenylalanine derivatives: structural insights from solution and solid state studies

Water soluble fibers of PEGylated tetra-phenylalanine (F4), chemically modified at the N-terminus with the DOTA chelating agent, have been proposed as innovative contrast agent (CA) in Magnetic Resonance Imaging (MRI) upon complexation of the gadolinium ion. An in-depth structural characterization o...

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Detalles Bibliográficos
Autores principales: Diaferia, Carlo, Mercurio, Flavia Anna, Giannini, Cinzia, Sibillano, Teresa, Morelli, Giancarlo, Leone, Marilisa, Accardo, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879547/
https://www.ncbi.nlm.nih.gov/pubmed/27220817
http://dx.doi.org/10.1038/srep26638