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TMPyP4 promotes cancer cell migration at low doses, but induces cell death at high doses

TMPyP4 is widely considered as a potential photosensitizer in photodynamic therapy and a G-quadruplex stabilizer for telomerase-based cancer therapeutics. However, its biological effects including a possible adverse-effect are poorly understood. In this study, whole genome RNA-seq analysis was used...

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Detalles Bibliográficos
Autores principales: Zheng, Xiao-Hui, Nie, Xin, Liu, Hai-Ying, Fang, Yi-Ming, Zhao, Yong, Xia, Li-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879555/
https://www.ncbi.nlm.nih.gov/pubmed/27221067
http://dx.doi.org/10.1038/srep26592