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Quantitative PPARγ expression affects the balance between tolerance and immunity

PPARγ modulates energy metabolism and inflammation. However, its specific functions in the balance of immunity in vivo have been explored incompletely. In this study, by the age of 14 mo, Pparg(C/−) mice with PPARγ expression at 25% of the normal level exhibited high autoantibody levels and develope...

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Detalles Bibliográficos
Autores principales: Liu, Ya-Hui, Tsai, Yau-Sheng, Lin, Shih-Chieh, Liao, Nan-Shih, Jan, Ming-Shiou, Liang, Chung-Tiang, Hsu, Shih-Wen, Chen, Wen-Chung, Sung, Junne-Ming, Maeda, Nobuyo, Tsai, Pei-Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879582/
https://www.ncbi.nlm.nih.gov/pubmed/27221351
http://dx.doi.org/10.1038/srep26646