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Quantitative PPARγ expression affects the balance between tolerance and immunity
PPARγ modulates energy metabolism and inflammation. However, its specific functions in the balance of immunity in vivo have been explored incompletely. In this study, by the age of 14 mo, Pparg(C/−) mice with PPARγ expression at 25% of the normal level exhibited high autoantibody levels and develope...
Autores principales: | Liu, Ya-Hui, Tsai, Yau-Sheng, Lin, Shih-Chieh, Liao, Nan-Shih, Jan, Ming-Shiou, Liang, Chung-Tiang, Hsu, Shih-Wen, Chen, Wen-Chung, Sung, Junne-Ming, Maeda, Nobuyo, Tsai, Pei-Jane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879582/ https://www.ncbi.nlm.nih.gov/pubmed/27221351 http://dx.doi.org/10.1038/srep26646 |
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