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Alterations in voltage-sensing of the mitochondrial permeability transition pore in ANT1-deficient cells

The probability of mitochondrial permeability transition (mPT) pore opening is inversely related to the magnitude of the proton electrochemical gradient. The module conferring sensitivity of the pore to this gradient has not been identified. We investigated mPT’s voltage-sensing properties elicited...

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Detalles Bibliográficos
Autores principales: Doczi, Judit, Torocsik, Beata, Echaniz-Laguna, Andoni, Mousson de Camaret, Bénédicte, Starkov, Anatoly, Starkova, Natalia, Gál, Aniko, Molnár, Mária J, Kawamata, Hibiki, Manfredi, Giovanni, Adam-Vizi, Vera, Chinopoulos, Christos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879635/
https://www.ncbi.nlm.nih.gov/pubmed/27221760
http://dx.doi.org/10.1038/srep26700