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Alterations in voltage-sensing of the mitochondrial permeability transition pore in ANT1-deficient cells
The probability of mitochondrial permeability transition (mPT) pore opening is inversely related to the magnitude of the proton electrochemical gradient. The module conferring sensitivity of the pore to this gradient has not been identified. We investigated mPT’s voltage-sensing properties elicited...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879635/ https://www.ncbi.nlm.nih.gov/pubmed/27221760 http://dx.doi.org/10.1038/srep26700 |