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MicroRNA deregulation and chemotaxis and phagocytosis impairment in Alzheimer's disease

INTRODUCTION: Mononuclear phagocytes play a critical role during Alzheimer's disease (AD) pathogenesis due to their contribution to innate immune responses and amyloid beta (Aβ) clearance mechanisms. METHODS: Blood-derived monocytes (BDMs) and monocyte-derived macrophages (MDMs) were isolated f...

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Detalles Bibliográficos
Autores principales: Guedes, Joana R., Santana, Isabel, Cunha, Catarina, Duro, Diana, Almeida, Maria R., Cardoso, Ana M., de Lima, Maria C. Pedroso, Cardoso, Ana L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879648/
https://www.ncbi.nlm.nih.gov/pubmed/27239545
http://dx.doi.org/10.1016/j.dadm.2015.11.004