Combinations of Oseltamivir and T-705 Extend the Treatment Window for Highly Pathogenic Influenza A(H5N1) Virus Infection in Mice

Current anti-influenza therapy depends on administering drugs soon after infection, which is often impractical. We assessed whether combinations of oseltamivir (a neuraminidase inhibitor) and T-705 (a nonspecific inhibitor of viral polymerases) could extend the window for treating lethal infection w...

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Detalles Bibliográficos
Autores principales: Marathe, Bindumadhav M., Wong, Sook-San, Vogel, Peter, Garcia-Alcalde, Fernando, Webster, Robert G., Webby, Richard J., Najera, Isabel, Govorkova, Elena A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879667/
https://www.ncbi.nlm.nih.gov/pubmed/27221530
http://dx.doi.org/10.1038/srep26742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879667/
https://www.ncbi.nlm.nih.gov/pubmed/27221530
http://dx.doi.org/10.1038/srep26742

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