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Combinations of Oseltamivir and T-705 Extend the Treatment Window for Highly Pathogenic Influenza A(H5N1) Virus Infection in Mice
Current anti-influenza therapy depends on administering drugs soon after infection, which is often impractical. We assessed whether combinations of oseltamivir (a neuraminidase inhibitor) and T-705 (a nonspecific inhibitor of viral polymerases) could extend the window for treating lethal infection w...
Autores principales: | Marathe, Bindumadhav M., Wong, Sook-San, Vogel, Peter, Garcia-Alcalde, Fernando, Webster, Robert G., Webby, Richard J., Najera, Isabel, Govorkova, Elena A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879667/ https://www.ncbi.nlm.nih.gov/pubmed/27221530 http://dx.doi.org/10.1038/srep26742 |
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