Inhibition of myeloperoxidase oxidant production by N-acetyl lysyltyrosylcysteine amide reduces brain damage in a murine model of stroke

BACKGROUND: Oxidative stress plays an important and causal role in the mechanisms by which ischemia/reperfusion (I/R) injury increases brain damage after stroke. Accordingly, reducing oxidative stress has been proposed as a therapeutic strategy for limiting damage in the brain after stroke. Myeloper...

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Detalles Bibliográficos
Autores principales: Yu, Guoliang, Liang, Ye, Huang, Ziming, Jones, Deron W., Pritchard, Kirkwood A., Zhang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879722/
https://www.ncbi.nlm.nih.gov/pubmed/27220420
http://dx.doi.org/10.1186/s12974-016-0583-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879722/
https://www.ncbi.nlm.nih.gov/pubmed/27220420
http://dx.doi.org/10.1186/s12974-016-0583-x

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