Genetic Polymorphisms of Transcription Factor NRF2 and of its Host Gene Sulfiredoxin (SRXN1) are Associated with Cerebrovascular Disease in a Finnish Cohort, the TAMRISK Study

Oxidative stress is involved in the pathophysiology of many cardiovascular disorders, such as hypertension and atherosclerosis. NRF2 is the primary transcriptional regulator of several antioxidant genes, including that of sulfiredoxin (SRXN1). The association of genotypes of NRF2 and SRXN1 with card...

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Detalles Bibliográficos
Autores principales: Kunnas, Tarja, Määttä, Kirsi, Nikkari, Seppo T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879764/
https://www.ncbi.nlm.nih.gov/pubmed/27226772
http://dx.doi.org/10.7150/ijms.14849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879764/
https://www.ncbi.nlm.nih.gov/pubmed/27226772
http://dx.doi.org/10.7150/ijms.14849

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