Silencing the Nucleocytoplasmic O-GlcNAc Transferase Reduces Proliferation, Adhesion, and Migration of Cancer and Fetal Human Colon Cell Lines

The post-translational modification of proteins by O-linked β-N-acetylglucosamine (O-GlcNAc) is regulated by a unique couple of enzymes. O-GlcNAc transferase (OGT) transfers the GlcNAc residue from UDP-GlcNAc, the final product of the hexosamine biosynthetic pathway (HBP), whereas O-GlcNAcase (OGA)...

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Detalles Bibliográficos
Autores principales: Steenackers, Agata, Olivier-Van Stichelen, Stéphanie, Baldini, Steffi F., Dehennaut, Vanessa, Toillon, Robert-Alain, Le Bourhis, Xuefen, El Yazidi-Belkoura, Ikram, Lefebvre, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879930/
https://www.ncbi.nlm.nih.gov/pubmed/27252680
http://dx.doi.org/10.3389/fendo.2016.00046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879930/
https://www.ncbi.nlm.nih.gov/pubmed/27252680
http://dx.doi.org/10.3389/fendo.2016.00046

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