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Synaptic activation of ribosomal protein S6 phosphorylation occurs locally in activated dendritic domains

Previous studies have shown that induction of long-term potentiation (LTP) induces phosphorylation of ribosomal protein S6 (rpS6) in postsynaptic neurons, but the functional significance of rpS6 phosphorylation is poorly understood. Here, we show that synaptic stimulation that induces perforant path...

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Detalles Bibliográficos
Autores principales: Pirbhoy, Patricia Salgado, Farris, Shannon, Steward, Oswald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880148/
https://www.ncbi.nlm.nih.gov/pubmed/27194793
http://dx.doi.org/10.1101/lm.041947.116