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Feedback mechanisms control coexistence in a stem cell model of acute myeloid leukaemia

Haematopoietic stem cell dynamics regulate healthy blood cell production and are disrupted during leukaemia. Competition models of cellular species help to elucidate stem cell dynamics in the bone marrow microenvironment (or niche), and to determine how these dynamics impact leukaemia progression. H...

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Detalles Bibliográficos
Autores principales: Crowell, Helena L., MacLean, Adam L., Stumpf, Michael P.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880151/
https://www.ncbi.nlm.nih.gov/pubmed/27130539
http://dx.doi.org/10.1016/j.jtbi.2016.04.002