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Feedback mechanisms control coexistence in a stem cell model of acute myeloid leukaemia
Haematopoietic stem cell dynamics regulate healthy blood cell production and are disrupted during leukaemia. Competition models of cellular species help to elucidate stem cell dynamics in the bone marrow microenvironment (or niche), and to determine how these dynamics impact leukaemia progression. H...
Autores principales: | Crowell, Helena L., MacLean, Adam L., Stumpf, Michael P.H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880151/ https://www.ncbi.nlm.nih.gov/pubmed/27130539 http://dx.doi.org/10.1016/j.jtbi.2016.04.002 |
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