miR-190 Enhances HIF-Dependent Responses to Hypoxia in Drosophila by Inhibiting the Prolyl-4-hydroxylase Fatiga

Cellular and systemic responses to low oxygen levels are principally mediated by Hypoxia Inducible Factors (HIFs), a family of evolutionary conserved heterodimeric transcription factors, whose alpha- and beta-subunits belong to the bHLH-PAS family. In normoxia, HIFα is hydroxylated by specific proly...

Descripción completa

Detalles Bibliográficos
Autores principales: De Lella Ezcurra, Ana Laura, Bertolin, Agustina Paola, Kim, Kevin, Katz, Maximiliano Javier, Gándara, Lautaro, Misra, Tvisha, Luschnig, Stefan, Perrimon, Norbert, Melani, Mariana, Wappner, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880290/
https://www.ncbi.nlm.nih.gov/pubmed/27223464
http://dx.doi.org/10.1371/journal.pgen.1006073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880290/
https://www.ncbi.nlm.nih.gov/pubmed/27223464
http://dx.doi.org/10.1371/journal.pgen.1006073

Ejemplares similares