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The Influence of Hydroxylation on Maintaining CpG Methylation Patterns: A Hidden Markov Model Approach

DNA methylation and demethylation are opposing processes that when in balance create stable patterns of epigenetic memory. The control of DNA methylation pattern formation by replication dependent and independent demethylation processes has been suggested to be influenced by Tet mediated oxidation o...

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Detalles Bibliográficos
Autores principales: Giehr, Pascal, Kyriakopoulos, Charalampos, Ficz, Gabriella, Wolf, Verena, Walter, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880293/
https://www.ncbi.nlm.nih.gov/pubmed/27224554
http://dx.doi.org/10.1371/journal.pcbi.1004905