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The Influence of Hydroxylation on Maintaining CpG Methylation Patterns: A Hidden Markov Model Approach
DNA methylation and demethylation are opposing processes that when in balance create stable patterns of epigenetic memory. The control of DNA methylation pattern formation by replication dependent and independent demethylation processes has been suggested to be influenced by Tet mediated oxidation o...
Autores principales: | Giehr, Pascal, Kyriakopoulos, Charalampos, Ficz, Gabriella, Wolf, Verena, Walter, Jörn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880293/ https://www.ncbi.nlm.nih.gov/pubmed/27224554 http://dx.doi.org/10.1371/journal.pcbi.1004905 |
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