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Synthetic B-Cell Epitopes Eliciting Cross-Neutralizing Antibodies: Strategies for Future Dengue Vaccine

Dengue virus (DENV) is a major public health threat worldwide. A key element in protection from dengue fever is the neutralising antibody response. Anti-dengue IgG purified from DENV-2 infected human sera showed reactivity against several peptides when evaluated by ELISA and epitope extraction techn...

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Detalles Bibliográficos
Autores principales: Ramanathan, Babu, Poh, Chit Laa, Kirk, Kristin, McBride, William John Hannan, Aaskov, John, Grollo, Lara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880327/
https://www.ncbi.nlm.nih.gov/pubmed/27223692
http://dx.doi.org/10.1371/journal.pone.0155900