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Involvement of TGF-β1/Smad3 Signaling in Carbon Tetrachloride-Induced Acute Liver Injury in Mice

Transforming growth factor-beta1 (TGF-β1) is a major factor in pathogenesis of chronic hepatic injury. Carbon tetrachloride (CCl(4)) is a liver toxicant, and CCl(4)-induced liver injury in mouse is a classical animal model of chemical liver injury. However, it is still unclear whether TGF-β1 is invo...

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Detalles Bibliográficos
Autores principales: Niu, Liman, Cui, Xueling, Qi, Yan, Xie, Dongxue, Wu, Qian, Chen, Xinxin, Ge, Jingyan, Liu, Zhonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880333/
https://www.ncbi.nlm.nih.gov/pubmed/27224286
http://dx.doi.org/10.1371/journal.pone.0156090