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Sphingosine-1-Phosphate Receptor 2 Regulates Proinflammatory Cytokine Production and Osteoclastogenesis

Sphingosine-1-phosphate receptor 2 (S1PR2) couples with the Gi, Gq, and G(12/13) group of proteins, which modulate an array of cellular signaling pathways and affect immune responses to multiple stimuli. In this study, we demonstrated that knockdown of S1PR2 by a specific S1PR2 shRNA lentiviral vect...

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Detalles Bibliográficos
Autor principal: Yu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880337/
https://www.ncbi.nlm.nih.gov/pubmed/27224249
http://dx.doi.org/10.1371/journal.pone.0156303