Evolution of Thermophilic DNA Polymerases for the Recognition and Amplification of C2’-Modified DNA

The PCR amplification of oligonucleotides enables the evolution of sequences called aptamers that bind specific targets with antibody-like affinity. However, the use of these aptamers is limited in many applications by nuclease-mediated degradation. In contrast, oligonucleotides that are modified at...

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Detalles Bibliográficos
Autores principales: Chen, Tingjian, Hongdilokkul, Narupat, Liu, Zhixia, Adhikary, Ramkrishna, Tsuen, Shujian S., Romesberg, Floyd E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880425/
https://www.ncbi.nlm.nih.gov/pubmed/27219699
http://dx.doi.org/10.1038/nchem.2493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880425/
https://www.ncbi.nlm.nih.gov/pubmed/27219699
http://dx.doi.org/10.1038/nchem.2493

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