Cargando…
Evolution of Thermophilic DNA Polymerases for the Recognition and Amplification of C2’-Modified DNA
The PCR amplification of oligonucleotides enables the evolution of sequences called aptamers that bind specific targets with antibody-like affinity. However, the use of these aptamers is limited in many applications by nuclease-mediated degradation. In contrast, oligonucleotides that are modified at...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880425/ https://www.ncbi.nlm.nih.gov/pubmed/27219699 http://dx.doi.org/10.1038/nchem.2493 |