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Mosaic 13q14 deletions in peripheral leukocytes of non-hematologic cancer cases and healthy controls

Loss of 13q14.3 is a chromosomal event found in approximately 50 percent of B-cell chronic lymphocytic leukemia (CLL) and monoclonal B-cell lymphocytosis (MBL) cases. Surveys of somatic alterations in solid tumors have shown sporadic 13q14.3 loss in many different tumor types, but not at high freque...

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Detalles Bibliográficos
Autores principales: Machiela, Mitchell J., Zhou, Weiyin, Caporaso, Neil, Dean, Michael, Gapstur, Susan M., Goldin, Lynn, Stevens, Victoria L., Yeager, Meredith, Chanock, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880507/
https://www.ncbi.nlm.nih.gov/pubmed/26763882
http://dx.doi.org/10.1038/jhg.2015.166