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Dynamic Regulation of APE1/Ref-1 as a Therapeutic Target Protein

Apurinic/apyrimidinic endonuclease 1/redox factor-1 (APE1/Ref-1) is a multifunctional protein that plays a central role in the cellular response to DNA damage and redox regulation against oxidative stress. APE1/Ref-1 functions in the DNA base excision repair pathway, the redox regulation of several...

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Detalles Bibliográficos
Autores principales: Choi, Sunga, Joo, Hee Kyoung, Jeon, Byeong Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chonnam National University Medical School 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880582/
https://www.ncbi.nlm.nih.gov/pubmed/27231670
http://dx.doi.org/10.4068/cmj.2016.52.2.75