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Dynamic Regulation of APE1/Ref-1 as a Therapeutic Target Protein
Apurinic/apyrimidinic endonuclease 1/redox factor-1 (APE1/Ref-1) is a multifunctional protein that plays a central role in the cellular response to DNA damage and redox regulation against oxidative stress. APE1/Ref-1 functions in the DNA base excision repair pathway, the redox regulation of several...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chonnam National University Medical School
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880582/ https://www.ncbi.nlm.nih.gov/pubmed/27231670 http://dx.doi.org/10.4068/cmj.2016.52.2.75 |