Immunogenicity and efficacy of the novel cancer vaccine based on simian adenovirus and MVA vectors alone and in combination with PD-1 mAb in a mouse model of prostate cancer

Prostate cancer possesses several characteristics that make it a suitable candidate for immunotherapy; however, prostate cancer vaccines to date demonstrate modest efficacy and low immunogenicity. The goal of the present pre-clinical study was to explore the immunogenic properties and protective eff...

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Detalles Bibliográficos
Autores principales: Cappuccini, Federica, Stribbling, Stephen, Pollock, Emily, Hill, Adrian V. S., Redchenko, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880633/
https://www.ncbi.nlm.nih.gov/pubmed/27052571
http://dx.doi.org/10.1007/s00262-016-1831-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880633/
https://www.ncbi.nlm.nih.gov/pubmed/27052571
http://dx.doi.org/10.1007/s00262-016-1831-8

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