Carbonic anhydrase IX is a marker of hypoxia and correlates with higher Gleason scores and ISUP grading in prostate cancer

BACKGROUND: Carbonic anhydrase IX is a member of α-carbonic anhydrases that is preferentially expressed in solid tumors. It enables bicarbonate transport across the plasma membrane, neutralizing intracellular pH and conferring to cancer cells a survival advantage in hypoxic/acidic microenvironments....

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Detalles Bibliográficos
Autores principales: Ambrosio, Maria Raffaella, Di Serio, Claudia, Danza, Giovanna, Rocca, Bruno Jim, Ginori, Alessandro, Prudovsky, Igor, Marchionni, Niccolò, del Vecchio, Maria Teresa, Tarantini, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880832/
https://www.ncbi.nlm.nih.gov/pubmed/27225200
http://dx.doi.org/10.1186/s13000-016-0495-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880832/
https://www.ncbi.nlm.nih.gov/pubmed/27225200
http://dx.doi.org/10.1186/s13000-016-0495-1

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