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Polymorphisms of the ELANE Gene Promoter Region in End-Stage Chronic Kidney Disease Patients

End-stage renal disease (ESRD) patients have a high mortality rate that exceeds that of non-ESRD population. The hemodialysis procedure induces neutrophil activation and elastase release, which might have a role in the inflammatory process and in the development of oxidative stress. The ELANE gene e...

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Detalles Bibliográficos
Autores principales: Fernandes, Rafael, Freitas, Bruno, Miranda, Vasco, Costa, Elísio, Santos-Silva, Alice, Bronze-da-Rocha, Elsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880837/
https://www.ncbi.nlm.nih.gov/pubmed/27136588
http://dx.doi.org/10.3390/genes7050017