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Characterization of Adenomatous Polyposis Coli Protein Dynamics and Localization at the Centrosome

The adenomatous polyposis coli (APC) tumor suppressor is a multifunctional regulator of Wnt signaling and acts as a mobile scaffold at different cellular sites. APC was recently found to stimulate microtubule (MT) growth at the interphase centrosome; however, little is known about its dynamics and l...

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Detalles Bibliográficos
Autores principales: Lui, Christina, Mok, Myth T. S., Henderson, Beric R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880864/
https://www.ncbi.nlm.nih.gov/pubmed/27144584
http://dx.doi.org/10.3390/cancers8050047