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Characterization of Adenomatous Polyposis Coli Protein Dynamics and Localization at the Centrosome
The adenomatous polyposis coli (APC) tumor suppressor is a multifunctional regulator of Wnt signaling and acts as a mobile scaffold at different cellular sites. APC was recently found to stimulate microtubule (MT) growth at the interphase centrosome; however, little is known about its dynamics and l...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880864/ https://www.ncbi.nlm.nih.gov/pubmed/27144584 http://dx.doi.org/10.3390/cancers8050047 |