Systematic analysis of mutation distribution in three dimensional protein structures identifies cancer driver genes

Protein tertiary structure determines molecular function, interaction, and stability of the protein, therefore distribution of mutation in the tertiary structure can facilitate the identification of new driver genes in cancer. To analyze mutation distribution in protein tertiary structures, we appli...

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Detalles Bibliográficos
Autores principales: Fujimoto, Akihiro, Okada, Yukinori, Boroevich, Keith A., Tsunoda, Tatsuhiko, Taniguchi, Hiroaki, Nakagawa, Hidewaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880911/
https://www.ncbi.nlm.nih.gov/pubmed/27225414
http://dx.doi.org/10.1038/srep26483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880911/
https://www.ncbi.nlm.nih.gov/pubmed/27225414
http://dx.doi.org/10.1038/srep26483

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