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Systematic analysis of mutation distribution in three dimensional protein structures identifies cancer driver genes
Protein tertiary structure determines molecular function, interaction, and stability of the protein, therefore distribution of mutation in the tertiary structure can facilitate the identification of new driver genes in cancer. To analyze mutation distribution in protein tertiary structures, we appli...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880911/ https://www.ncbi.nlm.nih.gov/pubmed/27225414 http://dx.doi.org/10.1038/srep26483 |