Genomic, Lipidomic and Metabolomic Analysis of Cyclooxygenase-null Cells: Eicosanoid Storm, Cross Talk, and Compensation by COX-1

The constitutively-expressed cyclooxygenase 1 (COX-1) and the inducible COX-2 are both involved in the conversion of arachidonic acid (AA) to prostaglandins (PGs). However, the functional roles of COX-1 at the cellular level remain unclear. We hypothesized that by comparing differential gene express...

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Detalles Bibliográficos
Autores principales: Islam, Abul B.M.M.K., Dave, Mandar, Amin, Sonia, Jensen, Roderick V., Amin, Ashok R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880957/
https://www.ncbi.nlm.nih.gov/pubmed/27012456
http://dx.doi.org/10.1016/j.gpb.2014.09.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880957/
https://www.ncbi.nlm.nih.gov/pubmed/27012456
http://dx.doi.org/10.1016/j.gpb.2014.09.005

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