Enhanced whole exome sequencing by higher DNA insert lengths

BACKGROUND: Whole exome sequencing (WES) has been proven to serve as a valuable basis for various applications such as variant calling and copy number variation (CNV) analyses. For those analyses the read coverage should be optimally balanced throughout protein coding regions at sufficient read dept...

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Detalles Bibliográficos
Autores principales: Pommerenke, Claudia, Geffers, Robert, Bunk, Boyke, Bhuju, Sabin, Eberth, Sonja, Drexler, Hans G., Quentmeier, Hilmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880973/
https://www.ncbi.nlm.nih.gov/pubmed/27225215
http://dx.doi.org/10.1186/s12864-016-2698-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880973/
https://www.ncbi.nlm.nih.gov/pubmed/27225215
http://dx.doi.org/10.1186/s12864-016-2698-y

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