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Pharmacologic rationale for the NK1R antagonist, aprepitant as adjunctive therapy in HIV
BACKGROUND: Many HIV infected individuals with suppressed viral loads experience chronic immune activation frequently developing neurological impairment designated as HIV associated neurocognitive disorder (HAND). Adjunctive therapies may reduce HIV associated inflammation and therefore decrease the...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880976/ https://www.ncbi.nlm.nih.gov/pubmed/27230663 http://dx.doi.org/10.1186/s12967-016-0904-y |