Pharmacologic rationale for the NK1R antagonist, aprepitant as adjunctive therapy in HIV

BACKGROUND: Many HIV infected individuals with suppressed viral loads experience chronic immune activation frequently developing neurological impairment designated as HIV associated neurocognitive disorder (HAND). Adjunctive therapies may reduce HIV associated inflammation and therefore decrease the...

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Detalles Bibliográficos
Autores principales: Barrett, Jeffrey S., Spitsin, Sergei, Moorthy, Ganesh, Barrett, Kyle, Baker, Kate, Lackner, Andrew, Tulic, Florin, Winters, Angela, Evans, Dwight L., Douglas, Steven D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880976/
https://www.ncbi.nlm.nih.gov/pubmed/27230663
http://dx.doi.org/10.1186/s12967-016-0904-y

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