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Transcriptome analysis of Streptococcus pneumoniae treated with the designed antimicrobial peptides, DM3

In our previous studies, we generated a short 13 amino acid antimicrobial peptide (AMP), DM3, showing potent antipneumococcal activity in vitro and in vivo. Here we analyse the underlying mechanisms of action using Next-Generation transcriptome sequencing of penicillin (PEN)-resistant and PEN-suscep...

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Detalles Bibliográficos
Autores principales: Le, Cheng-Foh, Gudimella, Ranganath, Razali, Rozaimi, Manikam, Rishya, Sekaran, Shamala Devi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881017/
https://www.ncbi.nlm.nih.gov/pubmed/27225022
http://dx.doi.org/10.1038/srep26828