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Improved intra-array and interarray normalization of peptide microarray phosphorylation for phosphorylome and kinome profiling by rational selection of relevant spots

Massive parallel analysis using array technology has become the mainstay for analysis of genomes and transcriptomes. Analogously, the predominance of phosphorylation as a regulator of cellular metabolism has fostered the development of peptide arrays of kinase consensus substrates that allow the cha...

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Detalles Bibliográficos
Autores principales: Scholma, Jetse, Fuhler, Gwenny M., Joore, Jos, Hulsman, Marc, Schivo, Stefano, List, Alan F., Reinders, Marcel J. T., Peppelenbosch, Maikel P., Post, Janine N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881024/
https://www.ncbi.nlm.nih.gov/pubmed/27225531
http://dx.doi.org/10.1038/srep26695