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CRISPR/Cas9-Mediated Immunity to Geminiviruses: Differential Interference and Evasion

The CRISPR/Cas9 system has recently been used to confer molecular immunity against several eukaryotic viruses, including plant DNA geminiviruses. Here, we provide a detailed analysis of the efficiencies of targeting different coding and non-coding sequences in the genomes of multiple geminiviruses....

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Detalles Bibliográficos
Autores principales: Ali, Zahir, Ali, Shakila, Tashkandi, Manal, Zaidi, Syed Shan-e-Ali, Mahfouz, Magdy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881029/
https://www.ncbi.nlm.nih.gov/pubmed/27225592
http://dx.doi.org/10.1038/srep26912