κ-Opioid Receptor Stimulation Improves Endothelial Function via Akt-stimulated NO Production in Hyperlipidemic Rats

This study was designed to investigate the effect of U50,488H (a selective κ-opioid receptor agonist) on endothelial function impaired by hyperlipidemia and to determine the role of Akt-stimulated NO production in it. Hyperlipidemic model was established by feeding rats with a high-fat diet for 14 w...

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Detalles Bibliográficos
Autores principales: Tian, Fei, Zheng, Xu-Yang, Li, Juan, Zhang, Shu-Miao, Feng, Na, Guo, Hai-Tao, Jia, Min, Wang, Yue-Min, Fan, Rong, Pei, Jian-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881032/
https://www.ncbi.nlm.nih.gov/pubmed/27226238
http://dx.doi.org/10.1038/srep26807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881032/
https://www.ncbi.nlm.nih.gov/pubmed/27226238
http://dx.doi.org/10.1038/srep26807

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