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Impact of Different Promoters on Episomal Vectors Harbouring Characteristic Motifs of Matrix Attachment Regions

We previously demonstrated that the characteristic sequence of matrix attachment regions (MARs) allows transgenes to be maintained episomally in CHO cells. In the present study, six commonly used promoters from human cytomegalovirus major immediate-early (CMV), simian vacuolating virus 40 (SV40), Ro...

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Detalles Bibliográficos
Autores principales: Wang, Xiao-Yin, Zhang, Jun-He, Zhang, Xi, Sun, Qiu-Li, Zhao, Chun-Peng, Wang, Tian-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881036/
https://www.ncbi.nlm.nih.gov/pubmed/27226236
http://dx.doi.org/10.1038/srep26446