Cargando…

Impact of Different Promoters on Episomal Vectors Harbouring Characteristic Motifs of Matrix Attachment Regions

We previously demonstrated that the characteristic sequence of matrix attachment regions (MARs) allows transgenes to be maintained episomally in CHO cells. In the present study, six commonly used promoters from human cytomegalovirus major immediate-early (CMV), simian vacuolating virus 40 (SV40), Ro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Xiao-Yin, Zhang, Jun-He, Zhang, Xi, Sun, Qiu-Li, Zhao, Chun-Peng, Wang, Tian-Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881036/ https://www.ncbi.nlm.nih.gov/pubmed/27226236 http://dx.doi.org/10.1038/srep26446

Ejemplares similares

Shortened nuclear matrix attachment regions are sufficient for replication and maintenance of episomes in mammalian cells
por: Wang, Xiao-Yin, et al.
Publicado: (2019)

The EF‐1α promoter maintains high‐level transgene expression from episomal vectors in transfected CHO‐K1 cells
por: Wang, Xiaoyin, et al.
Publicado: (2017)

Stable S/MAR-based episomal vectors are regulated at the chromatin level
por: Tessadori, Federico, et al.
Publicado: (2010)

Advances in the Development and the Applications of Nonviral, Episomal Vectors for Gene Therapy
por: Mulia, Grace Elizabeth, et al.
Publicado: (2021)

Effect of promoter, promoter mutation and enhancer on transgene expression mediated by episomal vectors in transfected HEK293, Chang liver and primary cells
por: Xu, Zhong-Jie, et al.
Publicado: (2019)

Inducible microRNA expression by an all-in-one episomal vector system
por: Epanchintsev, Alexey, et al.
Publicado: (2006)

Episomes and Transposases—Utilities to Maintain Transgene Expression from Nonviral Vectors
por: Kreppel, Florian, et al.
Publicado: (2022)

Enhancers Improve the AID-Induced Hypermutation in Episomal Vector for Antibody Affinity Maturation in Mammalian Cell Display
por: Chen, Chuan, et al.
Publicado: (2018)

Bacterial episomes and plasmids;
Publicado: (1969)

Generation of a tumor- and tissue-specific episomal non-viral vector system
por: Haase, Rudolf, et al.
Publicado: (2013)

Genetic modification of dividing cells using episomally maintained S/MAR DNA vectors
por: Wong, Suet-Ping, et al.
Publicado: (2013)

Sonodelivery Facilitates Sustained Luciferase Expression from an Episomal Vector in Skeletal Muscle
por: Figueiredo Neto, Manoel, et al.
Publicado: (2015)

The IS2 Element Improves Transcription Efficiency of Integration-Deficient Lentiviral Vector Episomes
por: Sánchez-Hernández, Sabina, et al.
Publicado: (2018)

Development of an RNA Virus-Based Episomal Vector Capable of Switching Transgene Expression
por: Yamamoto, Yusuke, et al.
Publicado: (2019)

Gene Augmentation of CHM Using Non-Viral Episomal Vectors in Models of Choroideremia
por: Toualbi, Lyes, et al.
Publicado: (2023)

Matrix attachment region combinations increase transgene expression in transfected Chinese hamster ovary cells
por: Zhao, Chun-Peng, et al.
Publicado: (2017)

Cervical cancer subtypes harbouring integrated and/or episomal HPV16 portray distinct molecular phenotypes based on transcriptome profiling of mRNAs and miRNAs
por: Mandal, Paramita, et al.
Publicado: (2019)

Stable transformation of an episomal protein-tagging shuttle vector in the piscine diplomonad Spironucleus vortens
por: Dawson, Scott C, et al.
Publicado: (2008)

Stringent doxycycline-dependent control of gene activities using an episomal one-vector system
por: Bornkamm, Georg W., et al.
Publicado: (2005)

In vivo biodistribution analysis of transmission competent and defective RNA virus-based episomal vector
por: Komatsu, Yumiko, et al.
Publicado: (2020)

Topoisomerase Inhibitors Increase Episomal DNA Expression by Inducing the Integration of Episomal DNA in Hepatic Cells
por: Gómez-Moreno, Andoni, et al.
Publicado: (2023)

pEPito: a significantly improved non-viral episomal expression vector for mammalian cells
por: Haase, Rudolf, et al.
Publicado: (2010)

An episomal CRISPR/Cas9 system to derive vector-free gene modified mammalian cells
por: Li, Linlin, et al.
Publicado: (2016)

Episomal Nonviral Gene Therapy Vectors Slow Progression of Atherosclerosis in a Model of Familial Hypercholesterolemia
por: Kerr, Alastair G, et al.
Publicado: (2016)

Epigenetic-scale comparison of human iPSCs generated by retrovirus, Sendai virus or episomal vectors
por: Nishino, Koichiro, et al.
Publicado: (2018)

An episomal DNA vector platform for the persistent genetic modification of pluripotent stem cells and their differentiated progeny
por: Roig-Merino, Alicia, et al.
Publicado: (2021)

Generation of Induced Pluripotent Stem Cells from Lymphoblastoid Cell Lines by Electroporation of Episomal Vectors
por: Kim, Myunghyun, et al.
Publicado: (2022)

Matrix attachment regions as targets for retroviral integration
por: Johnson, Chassidy N, et al.
Publicado: (2005)

The Role of Nuclear Matrix Attachment Regions in Plants
por: Allen, George C.
Publicado: (2009)

Transpositionally active episomal hAT elements
por: O'Brochta, David A, et al.
Publicado: (2009)

An episomal vector-based CRISPR/Cas9 system for highly efficient gene knockout in human pluripotent stem cells
por: Xie, Yifang, et al.
Publicado: (2017)

Genetic Modification of Cancer Cells Using Non-Viral, Episomal S/MAR Vectors for In Vivo Tumour Modelling
por: Argyros, Orestis, et al.
Publicado: (2012)

Plasmid-based generation of neural cells from human fibroblasts using non-integrating episomal vectors
por: Dai, Shao-Bing, et al.
Publicado: (2019)

Direct Conversion of Human Endothelial Cells Into Liver Cancer‐Forming Cells Using Nonintegrative Episomal Vectors
por: Goya, Takeshi, et al.
Publicado: (2022)

Designer diatom episomes delivered by bacterial conjugation
por: Karas, Bogumil J., et al.
Publicado: (2015)

Topological implications of DNA tumor viral episomes
por: Kim, Eui Tae, et al.
Publicado: (2022)

S/MAR sequence confers long-term mitotic stability on non-integrating lentiviral vector episomes without selection
por: Verghese, Santhosh Chakkaramakkil, et al.
Publicado: (2014)

Genetic reprogramming of human amniotic cells with episomal vectors: neural rosettes as sentinels in candidate selection for validation assays
por: Wilson, Patricia G., et al.
Publicado: (2014)

High-risk follicular lymphomas harbour more somatic mutations including those in the AID-motif
por: Tsukamoto, Taku, et al.
Publicado: (2017)

Author Correction: An episomal vector-based CRISPR/Cas9 system for highly efficient gene knockout in human pluripotent stem cells
por: Xie, Yifang, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_qh4plencufog8bckd0ljbuf81n