Glucocorticoid receptor isoforms direct distinct mitochondrial programs to regulate ATP production

The glucocorticoid receptor (GR), a nuclear receptor and major drug target, has a highly conserved minor splice variant, GRγ, which differs by a single arginine within the DNA binding domain. GRγ, which comprises 10% of all GR transcripts, is constitutively expressed and tightly conserved through ma...

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Detalles Bibliográficos
Autores principales: Morgan, David J., Poolman, Toryn M., Williamson, Andrew J. K., Wang, Zichen, Clark, Neil R., Ma’ayan, Avi, Whetton, Anthony D., Brass, Andrew, Matthews, Laura C., Ray, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881047/
https://www.ncbi.nlm.nih.gov/pubmed/27226058
http://dx.doi.org/10.1038/srep26419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881047/
https://www.ncbi.nlm.nih.gov/pubmed/27226058
http://dx.doi.org/10.1038/srep26419

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