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Histone acetyltransferases: challenges in targeting bi-substrate enzymes
Histone acetyltransferases (HATs) are epigenetic enzymes that install acetyl groups onto lysine residues of cellular proteins such as histones, transcription factors, nuclear receptors, and enzymes. HATs have been shown to play a role in diseases ranging from cancer and inflammatory diseases to neur...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881052/ https://www.ncbi.nlm.nih.gov/pubmed/27231488 http://dx.doi.org/10.1186/s13148-016-0225-2 |